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Shear stress induces noncanonical autophagy in intestinal epithelial monolayers
Flow of fluids through the gut, such as milk from a neonatal diet, generates a shear stress on the unilaminar epithelium lining the lumen. We report that exposure to physiological levels of fluid shear stress leads to the formation of large vacuoles, containing extracellular contents within polarizi...
Autores principales: | Kim, Sun Wook, Ehrman, Jonathan, Ahn, Mok-Ryeon, Kondo, Jumpei, Lopez, Andrea A. Mancheno, Oh, Yun Sik, Kim, Xander H., Crawley, Scott W., Goldenring, James R., Tyska, Matthew J., Rericha, Erin C., Lau, Ken S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662261/ https://www.ncbi.nlm.nih.gov/pubmed/28855375 http://dx.doi.org/10.1091/mbc.E17-01-0021 |
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