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Toll-Like Receptor Ligands and Interferon-γ Synergize for Induction of Antitumor M1 Macrophages

Tumor-associated macrophages may either promote or suppress tumor growth depending on their activation status. Interferon-γ (IFN-γ) has been identified as a key factor for inducing tumoricidal M1 phenotype in macrophages. However, it remains unclear whether IFN-γ is sufficient or if additional stimu...

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Detalles Bibliográficos
Autores principales: Müller, Elisabeth, Christopoulos, Panagiotis F., Halder, Sanjib, Lunde, Anna, Beraki, Kahsai, Speth, Martin, Øynebråten, Inger, Corthay, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662546/
https://www.ncbi.nlm.nih.gov/pubmed/29123526
http://dx.doi.org/10.3389/fimmu.2017.01383