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Host genotype and time dependent antigen presentation of viral peptides: predictions from theory
The rate of progression of HIV infected individuals to AIDS is known to vary with the genotype of the host, and is linked to their allele of human leukocyte antigen (HLA) proteins, which present protein degradation products at the cell surface to circulating T-cells. HLA alleles are associated with...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662608/ https://www.ncbi.nlm.nih.gov/pubmed/29084996 http://dx.doi.org/10.1038/s41598-017-14415-8 |