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Host genotype and time dependent antigen presentation of viral peptides: predictions from theory

The rate of progression of HIV infected individuals to AIDS is known to vary with the genotype of the host, and is linked to their allele of human leukocyte antigen (HLA) proteins, which present protein degradation products at the cell surface to circulating T-cells. HLA alleles are associated with...

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Detalles Bibliográficos
Autores principales: Eccleston, R. Charlotte, Coveney, Peter V., Dalchau, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662608/
https://www.ncbi.nlm.nih.gov/pubmed/29084996
http://dx.doi.org/10.1038/s41598-017-14415-8