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Proprotein convertase subtilisin/kexin type 9 (PCSK9) Deficiency is Protective Against Venous Thrombosis in Mice

The effect of lipid lowering on the incidence of deep venous thrombosis (DVT) is controversial. The purpose of this study was to determine the effect of proprotein convertase subtilisin/kexin type 9 (PCSK9) deficiency on development of DVT in mice. Pcsk9 deficient (pcsk9 (−/−)) and wild-type (WT) li...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Wang, Qian, Wang, Jintao, Guo, Chiao, Kleiman, Kyle, Meng, He, Knight, Jason S., Eitzman, Daniel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662614/
https://www.ncbi.nlm.nih.gov/pubmed/29084995
http://dx.doi.org/10.1038/s41598-017-14307-x