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Stress-induced nuclear accumulation is dispensable for Hog1-dependent gene expression and virulence in a fungal pathogen

Stress-activated protein kinase (SAPK) pathways are evolutionarily conserved eukaryotic signalling modules that are essential for the virulence of human pathogenic fungi. The Hog1 SAPK in Candida albicans is robustly phosphorylated in response to a number of host-imposed stresses, and is essential f...

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Detalles Bibliográficos
Autores principales: Day, Alison M., Herrero-de-Dios, Carmen M., MacCallum, Donna M., Brown, Alistair J. P., Quinn, Janet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662626/
https://www.ncbi.nlm.nih.gov/pubmed/29085028
http://dx.doi.org/10.1038/s41598-017-14756-4