Cargando…

The Effects of Medium Spiny Neuron Morphologcial Changes on Basal Ganglia Network under External Electric Field: A Computational Modeling Study

The damage of dopaminergic neurons that innervate the striatum has been considered to be the proximate cause of Parkinson's disease (PD). In the dopamine-denervated state, the loss of dendritic spines and the decrease of dendritic length may prevent medium spiny neuron (MSN) from receiving too...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiaohan, Liu, Shenquan, Zhan, Feibiao, Wang, Jing, Jiang, Xiaofang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662631/
https://www.ncbi.nlm.nih.gov/pubmed/29123477
http://dx.doi.org/10.3389/fncom.2017.00091