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NADPH oxidase 4 modulates hepatic responses to lipopolysaccharide mediated by Toll-like receptor-4

Chronic inflammation plays a key role in development of many liver diseases. Stimulation of Toll-like receptor 4 (TLR4) by bacterial lipopolysaccharide (LPS) initiates inflammation and promotes development of hepatocellular carcinoma and other liver diseases. NADPH oxidases contribute to LPS-induced...

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Detalles Bibliográficos
Autores principales: Singh, Anand, Koduru, Bhargav, Carlisle, Cameron, Akhter, Hasina, Liu, Rui-Ming, Schroder, Katrin, Brandes, Ralf P., Ojcius, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662726/
https://www.ncbi.nlm.nih.gov/pubmed/29085012
http://dx.doi.org/10.1038/s41598-017-14574-8