Cargando…

Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling

More effective use of targeted anti-cancer drugs depends on elucidating the connection between the molecular states induced by drug treatment and the cellular phenotypes controlled by these states, such as cytostasis and death. This is particularly true when mutation of a single gene is inadequate a...

Descripción completa

Detalles Bibliográficos
Autores principales: Niepel, Mario, Hafner, Marc, Duan, Qiaonan, Wang, Zichen, Paull, Evan O., Chung, Mirra, Lu, Xiaodong, Stuart, Joshua M., Golub, Todd R., Subramanian, Aravind, Ma’ayan, Avi, Sorger, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662764/
https://www.ncbi.nlm.nih.gov/pubmed/29084964
http://dx.doi.org/10.1038/s41467-017-01383-w