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Distinct Effects of Monophosphoryl Lipid A, Oligodeoxynucleotide CpG, and Combination Adjuvants on Modulating Innate and Adaptive Immune Responses to Influenza Vaccination

Monophosphoryl lipid A (MPL) and oligodeoxynucleotide CpG are toll-like receptor (TLR) 4 and 9 agonist, respectively. Here, we investigated the effects of MPL, CpG, and combination adjuvants on stimulating in vitro dendritic cells (DCs), in vivo innate and adaptive immune responses, and protective e...

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Detalles Bibliográficos
Autores principales: Ko, Eun-Ju, Lee, Young-Tae, Lee, Youri, Kim, Ki-Hye, Kang, Sang-Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662782/
https://www.ncbi.nlm.nih.gov/pubmed/29093654
http://dx.doi.org/10.4110/in.2017.17.5.326