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Suppression of Inflammatory Demyelinaton and Axon Degeneration through Inhibiting Kv3 Channels

The development of neuroprotective and repair strategies for treating progressive multiple sclerosis (MS) requires new insights into axonal injury. 4-aminopyridine (4-AP), a blocker of voltage-gated K(+) (Kv) channels, is used in symptomatic treatment of progressive MS, but the underlying mechanism...

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Detalles Bibliográficos
Autores principales: Jukkola, Peter, Gu, Yuanzheng, Lovett-Racke, Amy E., Gu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662905/
https://www.ncbi.nlm.nih.gov/pubmed/29123469
http://dx.doi.org/10.3389/fnmol.2017.00344