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Suppression of Inflammatory Demyelinaton and Axon Degeneration through Inhibiting Kv3 Channels
The development of neuroprotective and repair strategies for treating progressive multiple sclerosis (MS) requires new insights into axonal injury. 4-aminopyridine (4-AP), a blocker of voltage-gated K(+) (Kv) channels, is used in symptomatic treatment of progressive MS, but the underlying mechanism...
Autores principales: | Jukkola, Peter, Gu, Yuanzheng, Lovett-Racke, Amy E., Gu, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662905/ https://www.ncbi.nlm.nih.gov/pubmed/29123469 http://dx.doi.org/10.3389/fnmol.2017.00344 |
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