Haplotype-specific MAPT exon 3 expression regulated by common intronic polymorphisms associated with Parkinsonian disorders

BACKGROUND: Genome wide association studies have identified microtubule associated protein tau (MAPT) H1 haplotype single nucleotide polymorphisms (SNPs) as leading common risk variants for Parkinson’s disease, progressive supranuclear palsy and corticobasal degeneration. The MAPT risk variants fall...

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Detalles Bibliográficos
Autores principales: Lai, Mang Ching, Bechy, Anne-Laure, Denk, Franziska, Collins, Emma, Gavriliouk, Maria, Zaugg, Judith B., Ryan, Brent J., Wade-Martins, Richard, Caffrey, Tara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663040/
https://www.ncbi.nlm.nih.gov/pubmed/29084565
http://dx.doi.org/10.1186/s13024-017-0224-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663040/
https://www.ncbi.nlm.nih.gov/pubmed/29084565
http://dx.doi.org/10.1186/s13024-017-0224-6

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