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Expression of hypoxia inducible factor 1α and 2α and its association with vitamin C level in thyroid lesions
BACKGROUND: Cells adapt to hypoxia by transcriptional induction of genes that participate in regulation of angiogenesis, glucose metabolism and cell proliferation. The primary factors mediating cell response to low oxygen tension are hypoxia inducible factors (HIFs), oxygen-dependent transcription a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663109/ https://www.ncbi.nlm.nih.gov/pubmed/29084538 http://dx.doi.org/10.1186/s12929-017-0388-y |