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Expression of hypoxia inducible factor 1α and 2α and its association with vitamin C level in thyroid lesions

BACKGROUND: Cells adapt to hypoxia by transcriptional induction of genes that participate in regulation of angiogenesis, glucose metabolism and cell proliferation. The primary factors mediating cell response to low oxygen tension are hypoxia inducible factors (HIFs), oxygen-dependent transcription a...

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Detalles Bibliográficos
Autores principales: Jóźwiak, Paweł, Ciesielski, Piotr, Zaczek, Agnieszka, Lipińska, Anna, Pomorski, Lech, Wieczorek, Marek, Bryś, Magdalena, Forma, Ewa, Krześlak, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663109/
https://www.ncbi.nlm.nih.gov/pubmed/29084538
http://dx.doi.org/10.1186/s12929-017-0388-y