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Rewriting the transcriptome: adenosine-to-inosine RNA editing by ADARs

One of the most prevalent forms of post-transcritpional RNA modification is the conversion of adenosine nucleosides to inosine (A-to-I), mediated by the ADAR family of enzymes. The functional requirement and regulatory landscape for the majority of A-to-I editing events are, at present, uncertain. R...

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Detalles Bibliográficos
Autores principales: Walkley, Carl R., Li, Jin Billy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663115/
https://www.ncbi.nlm.nih.gov/pubmed/29084589
http://dx.doi.org/10.1186/s13059-017-1347-3