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Thy-1 interaction with Fas in lipid rafts regulates fibroblast apoptosis and lung injury resolution

Thy-1-negative lung fibroblasts are resistant to apoptosis. The mechanisms governing this process and its relevance to fibrotic remodeling remain poorly understood. By using either sorted or transfected lung fibroblasts, we found that Thy-1 expression is associated with downregulation of anti-apopto...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoqiu, Wong, Simon S., Taype, Carmen A., Kim, Jeeyeon, Shentu, Tzu-Pin, Espinoza, Celia R., Finley, Cameron, Bradley, John E., Head, Brian P., Patel, Hemal H., Mah, Emma J., Hagood, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663248/
https://www.ncbi.nlm.nih.gov/pubmed/28165468
http://dx.doi.org/10.1038/labinvest.2016.145