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Endothelial dysfunction is associated with activation of the type I interferon system and platelets in patients with systemic lupus erythematosus

OBJECTIVES: Endothelial dysfunction may be connected to cardiovascular disease (CVD) in systemic lupus erythematosus (SLE). Type I interferons (IFNs) are central in SLE pathogenesis and are suggested to induce both endothelial dysfunction and platelet activation. In this study, we investigated the i...

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Detalles Bibliográficos
Autores principales: Tydén, Helena, Lood, Christian, Gullstrand, Birgitta, Nielsen, Christoffer Tandrup, Heegaard, Niels H H, Kahn, Robin, Jönsen, Andreas, Bengtsson, Anders A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663269/
https://www.ncbi.nlm.nih.gov/pubmed/29119007
http://dx.doi.org/10.1136/rmdopen-2017-000508