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Vaccine adjuvant MF59 promotes the intranodal differentiation of antigen-loaded and activated monocyte-derived dendritic cells

MF59 is an oil-in-water emulsion adjuvant approved for human influenza vaccination in European Union. The mode of action of MF59 is not fully elucidated yet, but results from several years of investigation indicate that MF59 establishes an immunocompetent environment at injection site which promotes...

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Detalles Bibliográficos
Autores principales: Cioncada, Rossella, Maddaluno, Marcella, Vo, Hoa Thi My, Woodruff, Matthew, Tavarini, Simona, Sammicheli, Chiara, Tortoli, Marco, Pezzicoli, Alfredo, De Gregorio, Ennio, Carroll, Michael C., D’Oro, Ugo, Piccioli, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663329/
https://www.ncbi.nlm.nih.gov/pubmed/29088224
http://dx.doi.org/10.1371/journal.pone.0185843