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Real world data on young patients with high-risk diffuse large B-cell lymphoma treated with R-CHOP or R-CHOEP - MYC, BCL2 and BCL6 as prognostic biomarkers

BACKGROUND: Double expression of MYC and BCL2 proteins (DE) and double-hit MYC+BCL2/BCL6 translocations (DH) were established as important biomarkers in patients with diffuse large B-cell lymphoma (DLBCL) by the 2016 revision of the World Health Organization classification of lymphoid neoplasms. Whe...

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Detalles Bibliográficos
Autores principales: Pedersen, Mette Ølgod, Gang, Anne Ortved, Brown, Peter, Pedersen, Michael, Knudsen, Helle, Nielsen, Signe Ledou, Poulsen, Tim, Wirenfeldt Klausen, Tobias, Høgdall, Estrid, Nørgaard, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663399/
https://www.ncbi.nlm.nih.gov/pubmed/29088292
http://dx.doi.org/10.1371/journal.pone.0186983