Cargando…

Hepatectomy leads to loss of TRAIL-expressing liver NK cells via downregulation of the CXCL9-CXCR3 axis in mice

Liver-resident natural killer (NK) cells express TNF-related apoptosis-inducing ligand (TRAIL), a critical molecule for NK cell-mediated tumor cell killing. We previously reported that TRAIL expression in liver NK cells decreases markedly after hepatectomy; however, the mechanism underlying this dra...

Descripción completa

Detalles Bibliográficos
Autores principales: Yano, Takuya, Ohira, Masahiro, Nakano, Ryosuke, Tanaka, Yuka, Ohdan, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663402/
https://www.ncbi.nlm.nih.gov/pubmed/29088306
http://dx.doi.org/10.1371/journal.pone.0186997