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A homodimer interface without base pairs in an RNA mimic of red fluorescent protein

Corn, a 28-nucleotide RNA, induces yellow fluorescence of its cognate ligand (3,5-difluoro-4-hydroxybenzylidene-imidazolinone-2-oxime, DFHO) by >1000-fold. It was selected in vitro to overcome limitations of other fluorogenic RNAs, particularly rapid photobleaching. We now report the Corn-DFHO co...

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Detalles Bibliográficos
Autores principales: Warner, Katherine Deigan, Sjekloća, Ljiljana, Song, Wenjiao, Filonov, Grigory S., Jaffrey, Samie R., Ferré-D’Amaré, Adrian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663454/
https://www.ncbi.nlm.nih.gov/pubmed/28945234
http://dx.doi.org/10.1038/nchembio.2475