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Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation

The generation of precise synaptic connections between developing neurons is critical to the formation of functional neural circuits. Astrocyte-secreted glypican 4 induces formation of active excitatory synapses by recruiting AMPA glutamate receptors to the postsynaptic cell surface. We now identify...

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Detalles Bibliográficos
Autores principales: Farhy-Tselnicker, Isabella, van Casteren, Adriana C.M., Lee, Aletheia, Chang, Veronica T., Aricescu, A. Radu, Allen, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663462/
https://www.ncbi.nlm.nih.gov/pubmed/29024665
http://dx.doi.org/10.1016/j.neuron.2017.09.053