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Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation
The generation of precise synaptic connections between developing neurons is critical to the formation of functional neural circuits. Astrocyte-secreted glypican 4 induces formation of active excitatory synapses by recruiting AMPA glutamate receptors to the postsynaptic cell surface. We now identify...
Autores principales: | Farhy-Tselnicker, Isabella, van Casteren, Adriana C.M., Lee, Aletheia, Chang, Veronica T., Aricescu, A. Radu, Allen, Nicola J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663462/ https://www.ncbi.nlm.nih.gov/pubmed/29024665 http://dx.doi.org/10.1016/j.neuron.2017.09.053 |
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