COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin sorting signal

The COPI coat forms transport vesicles from the Golgi complex and plays a poorly defined role in endocytic trafficking. Here we show that COPI binds K63-linked polyubiquitin and this interaction is crucial for trafficking of a ubiquitinated yeast SNARE (Snc1). Snc1 is a v-SNARE that drives fusion of...

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Detalles Bibliográficos
Autores principales: Xu, Peng, Hankins, Hannah M, MacDonald, Chris, Erlinger, Samuel J, Frazier, Meredith N, Diab, Nicholas S, Piper, Robert C, Jackson, Lauren P, MacGurn, Jason A, Graham, Todd R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663479/
https://www.ncbi.nlm.nih.gov/pubmed/29058666
http://dx.doi.org/10.7554/eLife.28342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663479/
https://www.ncbi.nlm.nih.gov/pubmed/29058666
http://dx.doi.org/10.7554/eLife.28342

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