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Structural inhibition of dynamin-mediated membrane fission by endophilin

Dynamin, which mediates membrane fission during endocytosis, binds endophilin and other members of the Bin-Amphiphysin-Rvs (BAR) protein family. How endophilin influences endocytic membrane fission is still unclear. Here, we show that dynamin-mediated membrane fission is potently inhibited in vitro...

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Detalles Bibliográficos
Autores principales: Hohendahl, Annika, Talledge, Nathaniel, Galli, Valentina, Shen, Peter S, Humbert, Frédéric, De Camilli, Pietro, Frost, Adam, Roux, Aurélien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663480/
https://www.ncbi.nlm.nih.gov/pubmed/28933693
http://dx.doi.org/10.7554/eLife.26856