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Revisiting interaction specificity reveals neuronal and adipocyte Munc18 membrane fusion regulatory proteins differ in their binding interactions with partner SNARE Syntaxins

The efficient delivery of cellular cargo relies on the fusion of cargo-carrying vesicles with the correct membrane at the correct time. These spatiotemporal fusion events occur when SNARE proteins on the vesicle interact with cognate SNARE proteins on the target membrane. Regulatory Munc18 proteins...

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Detalles Bibliográficos
Autores principales: Christie, Michelle P., Hu, Shu-Hong, Whitten, Andrew E., Rehman, Asma, Jarrott, Russell J., King, Gordon J., Collins, Brett M., Martin, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663490/
https://www.ncbi.nlm.nih.gov/pubmed/29088285
http://dx.doi.org/10.1371/journal.pone.0187302