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TM4SF5 promotes metastatic behavior of cells in 3D extracellular matrix gels by reducing dependency on environmental cues

Transmembrane 4 L six family member 5 (TM4SF5) is highly expressed in hepatocellular carcinoma tissues and enhances migration in two-dimensional environments. Here, we investigated how TM4SF5 is involved in diverse pro-metastatic phenotypes in in vivo-like three-dimensional (3D) extracellular matrix...

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Detalles Bibliográficos
Autores principales: Song, Dae-Geun, Lee, Gyu-Ho, Nam, Seo Hee, Cheong, Jin-Gyu, Jeong, Doyoung, Lee, Seo-Jin, Pan, Cheol-Ho, Jung, Jae Woo, Kim, Hye-Jin, Ryu, Jihye, Kim, Ji Eon, Kim, Somi, Cho, Chang Yun, Kang, Min-Kyung, Lee, Kyung-Min, Lee, Jung Weon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663530/
https://www.ncbi.nlm.nih.gov/pubmed/29137358
http://dx.doi.org/10.18632/oncotarget.17644