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Novel mechanisms for crotonaldehyde-induced lung edema

BACKGROUND: Crotonaldehyde is a highly noxious α,β-unsaturated aldehyde in cigarette smoke that causes edematous acute lung injury. OBJECTIVE: To understand how crotonaldehyde impairs lung function, we examined its effects on human epithelial sodium channels (ENaC), which are major contributors to a...

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Detalles Bibliográficos
Autores principales: Li, Yue, Chang, Jianjun, Cui, Yong, Zhao, Runzhen, Ding, Yan, Hou, Yapeng, Zhou, Zhiyu, Ji, Hong-Long, Nie, Hongguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663532/
https://www.ncbi.nlm.nih.gov/pubmed/29137360
http://dx.doi.org/10.18632/oncotarget.17840