Glycolytic reprogramming through PCK2 regulates tumor initiation of prostate cancer cells

Tumor-initiating cells (TICs) play important roles in tumor progression and metastasis. Identifying the factors regulating TICs may open new avenues in cancer therapy. Here, we show that TIC-enriched prostate cancer cell clones use more glucose and secrete more lactate than TIC-low clones. We determ...

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Detalles Bibliográficos
Autores principales: Zhao, Jiangsha, Li, Jieran, Fan, Teresa W.M., Hou, Steven X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663539/
https://www.ncbi.nlm.nih.gov/pubmed/29137367
http://dx.doi.org/10.18632/oncotarget.18787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663539/
https://www.ncbi.nlm.nih.gov/pubmed/29137367
http://dx.doi.org/10.18632/oncotarget.18787

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