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Mitochondrial calcium uniporter as a target of microRNA-340 and promoter of metastasis via enhancing the Warburg effect

BACKGROUND: A shift from oxygen phosphorylation to aerobic glycolysis was known as the Warburg effect and a characteristic of cancer cell metabolism facilitating metastasis. Mitochondrial calcium uniporter (MCU), a key ion channel that mediates Ca(2+) uptake into mitochondria, was found to promote c...

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Detalles Bibliográficos
Autores principales: Yu, Changhui, Wang, Yuhao, Peng, Jiawen, Shen, Qiang, Chen, Mimi, Tang, Wei, Li, Xiumei, Cai, Chunqing, Wang, Bin, Cai, Shaoxi, Meng, Xiaojing, Zou, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663558/
https://www.ncbi.nlm.nih.gov/pubmed/29137386
http://dx.doi.org/10.18632/oncotarget.19747