A novel polyamine blockade therapy activates an anti-tumor immune response

Most tumors maintain elevated levels of polyamines to support their growth and survival. This study explores the anti-tumor effect of polyamine starvation via both inhibiting polyamine biosynthesis and blocking the upregulated import of polyamines into the tumor. We demonstrate that polyamine blocka...

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Detalles Bibliográficos
Autores principales: Alexander, Eric T., Minton, Allyson, Peters, Molly C., Phanstiel, Otto, Gilmour, Susan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663583/
https://www.ncbi.nlm.nih.gov/pubmed/29137411
http://dx.doi.org/10.18632/oncotarget.20493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663583/
https://www.ncbi.nlm.nih.gov/pubmed/29137411
http://dx.doi.org/10.18632/oncotarget.20493

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