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A novel polyamine blockade therapy activates an anti-tumor immune response

Most tumors maintain elevated levels of polyamines to support their growth and survival. This study explores the anti-tumor effect of polyamine starvation via both inhibiting polyamine biosynthesis and blocking the upregulated import of polyamines into the tumor. We demonstrate that polyamine blocka...

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Detalles Bibliográficos
Autores principales:	Alexander, Eric T., Minton, Allyson, Peters, Molly C., Phanstiel, Otto, Gilmour, Susan K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663583/ https://www.ncbi.nlm.nih.gov/pubmed/29137411 http://dx.doi.org/10.18632/oncotarget.20493

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