Ubiquitin conjugating enzyme E2 L3 promoted tumor growth of NSCLC through accelerating p27kip1 ubiquitination and degradation

The molecular pathogenesis of human lung cancer has not been completely clarified. Here, we reported that UBE2L3, a member of the ubiquitin-conjugating enzymes (E2s), were overexpressed in non-small-cell lung cancer (NSCLC) tissues compared with the non-tumor tissues. High expression of UBE2L3 was c...

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Detalles Bibliográficos
Autores principales: Ma, Xingjie, Zhao, Junjie, Yang, Fan, Liu, Haitao, Qi, Weibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663587/
https://www.ncbi.nlm.nih.gov/pubmed/29137415
http://dx.doi.org/10.18632/oncotarget.20449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663587/
https://www.ncbi.nlm.nih.gov/pubmed/29137415
http://dx.doi.org/10.18632/oncotarget.20449

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