Inhibition of retinoic acid receptor β signaling confers glycolytic dependence and sensitization to dichloroacetate in melanoma cells

Dysregulation of metabolism during melanoma progression is tightly associated with the acquisition of genetic and epigenetic alterations in regulators of metabolic pathways. Retinoic acid receptor beta (RARβ) is epigenetically silenced in a large proportion of melanomas, but a link between RARβ and...

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Detalles Bibliográficos
Autores principales: Abildgaard, Cecilie, Dahl, Christina, Abdul-Al, Ahmad, Christensen, Annette, Guldberg, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663589/
https://www.ncbi.nlm.nih.gov/pubmed/29137417
http://dx.doi.org/10.18632/oncotarget.20476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663589/
https://www.ncbi.nlm.nih.gov/pubmed/29137417
http://dx.doi.org/10.18632/oncotarget.20476

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