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Anti-angiogenic and anti-tumor effects of metronomic use of novel liposomal zoledronic acid depletes tumor-associated macrophages in triple negative breast cancer

Zoledronic acid (ZOL) has been used as an adjuvant therapy for breast cancer. It is suggested that ZOL might be associated with inhibition of macrophages, which in turn reduces tumor growth, metastasis and tumor angiogenesis. Moreover, metronomic therapy can inhibit tumor angiogenesis and tumor immu...

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Detalles Bibliográficos
Autores principales: Cai, Xin-Jun, Wang, Zeng, Cao, Jia-Wei, Ni, Jian-Jun, Xu, Ying-Ying, Yao, Jun, Xu, Hong, Liu, Fang, Yang, Gao-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663592/
https://www.ncbi.nlm.nih.gov/pubmed/29137420
http://dx.doi.org/10.18632/oncotarget.20539