GPER mediates differential effects of estrogen on colon cancer cell proliferation and migration under normoxic and hypoxic conditions

The estrogen receptor ERβ is the predominant ER subtype expressed in normal well-differentiated colonic epithelium. However, ERβ expression is lost under the hypoxic microenvironment as colorectal cancer (CRC) malignancy progresses. This raises questions about the role of signalling through other es...

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Detalles Bibliográficos
Autores principales: Bustos, Viviana, Nolan, Áine M., Nijhuis, Anke, Harvey, Harry, Parker, Alexandra, Poulsom, Richard, McBryan, Jean, Thomas, Warren, Silver, Andrew, Harvey, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663593/
https://www.ncbi.nlm.nih.gov/pubmed/29137421
http://dx.doi.org/10.18632/oncotarget.20653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663593/
https://www.ncbi.nlm.nih.gov/pubmed/29137421
http://dx.doi.org/10.18632/oncotarget.20653

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