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Pkm2 can enhance pluripotency in ESCs and promote somatic cell reprogramming to iPSCs

Aerobic glycolysis is one of the most important common characteristics in both cancer cells and stem cells. Metabolism switch has been discovered as an important early event in the process of reprogramming somatic cells to induced pluripotent stem cells (iPSCs). As a rate limiting kinase in glycolys...

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Detalles Bibliográficos
Autores principales: Qin, Shengtang, Yang, Danli, Chen, Kang, Li, Haolan, Zhang, Liqiang, Li, Yuan, Le, Rongrong, Li, Xiaojie, Gao, Shaorong, Kang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663594/
https://www.ncbi.nlm.nih.gov/pubmed/29137422
http://dx.doi.org/10.18632/oncotarget.20685