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Targeting the epitope spreader Pep19 by naïve human CD45RA(+) regulatory T cells dictates a distinct suppressive T cell fate in a novel form of immunotherapy

PURPOSE: Beyond the limited scope of non-specific polyclonal regulatory T cell (Treg)-based immunotherapy, which depends largely on serendipity, the present study explored a target Treg subset appropriate for the delivery of a novel epitope spreader Pep19 antigen as part of a sophisticated form of i...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Joo, Cha, Gil Sun, Joo, Ji-Young, Lee, Juyoun, Kim, Sung-Jo, Lee, Jeongae, Park, So Youn, Choi, Jeomil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Academy of Periodontology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663667/
https://www.ncbi.nlm.nih.gov/pubmed/29093987
http://dx.doi.org/10.5051/jpis.2017.47.5.292