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Generation of Insulin-Expressing Cells in Mouse Small Intestine by Pdx1, MafA, and BETA2/NeuroD

BACKGROUND: To develop surrogate insulin-producing cells for diabetes therapy, adult stem cells have been identified in various tissues and studied for their conversion into β-cells. Pancreatic progenitor cells are derived from the endodermal epithelium and formed in a manner similar to gut progenit...

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Detalles Bibliográficos
Autores principales: Lee, So-Hyun, Rhee, Marie, Kim, Ji-Won, Yoon, Kun-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663680/
https://www.ncbi.nlm.nih.gov/pubmed/29086539
http://dx.doi.org/10.4093/dmj.2017.41.5.405