Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity profiles

Plasmodium parasites have extensive needs from their host hepatocytes during the obligate liver stage of infection, yet there remains sparse knowledge of specific host regulators. Here we assess 34 host-targeted kinase inhibitors for their capacity to eliminate Plasmodium yoelii-infected hepatocytes...

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Detalles Bibliográficos
Autores principales: Arang, Nadia, Kain, Heather S., Glennon, Elizabeth K., Bello, Thomas, Dudgeon, Denali R., Walter, Emily N. F., Gujral, Taranjit S., Kaushansky, Alexis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663700/
https://www.ncbi.nlm.nih.gov/pubmed/29089541
http://dx.doi.org/10.1038/s41467-017-01345-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663700/
https://www.ncbi.nlm.nih.gov/pubmed/29089541
http://dx.doi.org/10.1038/s41467-017-01345-2

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