Novel Benzylidene Thiazolidinedione Derivatives as Partial PPARγ Agonists and their Antidiabetic Effects on Type 2 Diabetes

Peroxisome proliferator-activated receptor γ (PPARγ) has received significant attention as a key regulator of glucose and lipid homeostasis. In this study, we synthesized and tested a library of novel 5-benzylidene-thiazolidin-2,4-dione (BTZD) derivatives bearing a substituent on nitrogen of TZD nuc...

Descripción completa

Detalles Bibliográficos
Autores principales: Yasmin, Sabina, Capone, Fabio, Laghezza, Antonio, Piaz, Fabrizio Dal, Loiodice, Fulvio, Vijayan, Viswanathan, Devadasan, Velmurugan, Mondal, Susanta K., Atlı, Özlem, Baysal, Merve, Pattnaik, Ashok K., Jayaprakash, Venkatesan, Lavecchia, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663708/
https://www.ncbi.nlm.nih.gov/pubmed/29089569
http://dx.doi.org/10.1038/s41598-017-14776-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663708/
https://www.ncbi.nlm.nih.gov/pubmed/29089569
http://dx.doi.org/10.1038/s41598-017-14776-0

Ejemplares similares