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Novel Benzylidene Thiazolidinedione Derivatives as Partial PPARγ Agonists and their Antidiabetic Effects on Type 2 Diabetes

Peroxisome proliferator-activated receptor γ (PPARγ) has received significant attention as a key regulator of glucose and lipid homeostasis. In this study, we synthesized and tested a library of novel 5-benzylidene-thiazolidin-2,4-dione (BTZD) derivatives bearing a substituent on nitrogen of TZD nuc...

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Detalles Bibliográficos
Autores principales:	Yasmin, Sabina, Capone, Fabio, Laghezza, Antonio, Piaz, Fabrizio Dal, Loiodice, Fulvio, Vijayan, Viswanathan, Devadasan, Velmurugan, Mondal, Susanta K., Atlı, Özlem, Baysal, Merve, Pattnaik, Ashok K., Jayaprakash, Venkatesan, Lavecchia, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663708/ https://www.ncbi.nlm.nih.gov/pubmed/29089569 http://dx.doi.org/10.1038/s41598-017-14776-0

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