Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity

It is not known exactly where amyloid-β (Aβ) fibrils begin to accumulate in individuals with Alzheimer’s disease (AD). Recently, we showed that abnormal levels of Aβ42 in cerebrospinal fluid (CSF) can be detected before abnormal amyloid can be detected using PET in individuals with preclinical AD. U...

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Detalles Bibliográficos
Autores principales: Palmqvist, Sebastian, Schöll, Michael, Strandberg, Olof, Mattsson, Niklas, Stomrud, Erik, Zetterberg, Henrik, Blennow, Kaj, Landau, Susan, Jagust, William, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663717/
https://www.ncbi.nlm.nih.gov/pubmed/29089479
http://dx.doi.org/10.1038/s41467-017-01150-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663717/
https://www.ncbi.nlm.nih.gov/pubmed/29089479
http://dx.doi.org/10.1038/s41467-017-01150-x

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