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Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity
It is not known exactly where amyloid-β (Aβ) fibrils begin to accumulate in individuals with Alzheimer’s disease (AD). Recently, we showed that abnormal levels of Aβ42 in cerebrospinal fluid (CSF) can be detected before abnormal amyloid can be detected using PET in individuals with preclinical AD. U...
Autores principales: | Palmqvist, Sebastian, Schöll, Michael, Strandberg, Olof, Mattsson, Niklas, Stomrud, Erik, Zetterberg, Henrik, Blennow, Kaj, Landau, Susan, Jagust, William, Hansson, Oskar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663717/ https://www.ncbi.nlm.nih.gov/pubmed/29089479 http://dx.doi.org/10.1038/s41467-017-01150-x |
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