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Alzheimer’s disease and cigarette smoke components: effects of nicotine, PAHs, and Cd(II), Cr(III), Pb(II), Pb(IV) ions on amyloid-β peptide aggregation

Cigarette smoking is a significant risk factor for Alzheimer’s disease (AD), which is associated with extracellular brain deposits of amyloid plaques containing aggregated amyloid-β (Aβ) peptides. Aβ aggregation occurs via multiple pathways that can be influenced by various compounds. Here, we used...

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Detalles Bibliográficos
Autores principales: Wallin, Cecilia, Sholts, Sabrina B., Österlund, Nicklas, Luo, Jinghui, Jarvet, Jüri, Roos, Per M., Ilag, Leopold, Gräslund, Astrid, Wärmländer, Sebastian K. T. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663743/
https://www.ncbi.nlm.nih.gov/pubmed/29089568
http://dx.doi.org/10.1038/s41598-017-13759-5