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Macrophage migration inhibitory factor (MIF) modulates trophic signaling through interaction with serine protease HTRA1

Macrophage migration inhibitory factor (MIF), a small conserved protein, is abundant in the immune- and central nervous system (CNS). MIF has several receptors and binding partners that can modulate its action on a cellular level. It is upregulated in neurodegenerative diseases and cancer although i...

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Detalles Bibliográficos
Autores principales: Fex Svenningsen, Åsa, Löring, Svenja, Sørensen, Anna Lahn, Huynh, Ha Uyen Buu, Hjæresen, Simone, Martin, Nellie, Moeller, Jesper Bonnet, Elkjær, Maria Louise, Holmskov, Uffe, Illes, Zsolt, Andersson, Malin, Nielsen, Solveig Beck, Benedikz, Eirikur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663815/
https://www.ncbi.nlm.nih.gov/pubmed/28726057
http://dx.doi.org/10.1007/s00018-017-2592-z