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FcεRI γ-Chain Negatively Modulates Dectin-1 Responses in Dendritic Cells

The inhibitory effect of immunoreceptor tyrosine-based activation motif (ITAM)-containing adapters DAP12 and FcεRI γ-chain (FcRγ) has been found in many immune functions. Herein, we have further explored the role of these adapters in C-type lectin receptors response. We identified that FcRγ, but not...

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Detalles Bibliográficos
Autores principales: Pan, Yi-Gen, Yu, Yen-Ling, Lin, Chi-Chien, Lanier, Lewis L., Chu, Ching-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663849/
https://www.ncbi.nlm.nih.gov/pubmed/29163499
http://dx.doi.org/10.3389/fimmu.2017.01424