On-demand optogenetic activation of human stem-cell-derived neurons

The widespread application of human stem-cell-derived neurons for functional studies is impeded by complicated differentiation protocols, immaturity, and deficient optogene expression as stem cells frequently lose transgene expression over time. Here we report a simple but precise Cre-loxP-based str...

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Detalles Bibliográficos
Autores principales: Klapper, Simon D., Sauter, Evelyn J., Swiersy, Anka, Hyman, Max A. E., Bamann, Christian, Bamberg, Ernst, Busskamp, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663899/
https://www.ncbi.nlm.nih.gov/pubmed/29089561
http://dx.doi.org/10.1038/s41598-017-14827-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663899/
https://www.ncbi.nlm.nih.gov/pubmed/29089561
http://dx.doi.org/10.1038/s41598-017-14827-6

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