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On-demand optogenetic activation of human stem-cell-derived neurons
The widespread application of human stem-cell-derived neurons for functional studies is impeded by complicated differentiation protocols, immaturity, and deficient optogene expression as stem cells frequently lose transgene expression over time. Here we report a simple but precise Cre-loxP-based str...
Autores principales: | Klapper, Simon D., Sauter, Evelyn J., Swiersy, Anka, Hyman, Max A. E., Bamann, Christian, Bamberg, Ernst, Busskamp, Volker |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663899/ https://www.ncbi.nlm.nih.gov/pubmed/29089561 http://dx.doi.org/10.1038/s41598-017-14827-6 |
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