Calpain Inhibition Attenuates Adipose Tissue Inflammation and Fibrosis in Diet-induced Obese Mice

Adipose tissue macrophages have been proposed as a link between obesity and insulin resistance. However, the mechanisms underlying these processes are not completely defined. Calpains are calcium-dependent neutral cysteine proteases that modulate cellular function and have been implicated in various...

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Detalles Bibliográficos
Autores principales: Muniappan, Latha, Javidan, Aida, Jiang, Weihua, Mohammadmoradi, Shayan, Moorleghen, Jessica J., Katz, Wendy S., Balakrishnan, Anju, Howatt, Deborah A., Subramanian, Venkateswaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663911/
https://www.ncbi.nlm.nih.gov/pubmed/29089532
http://dx.doi.org/10.1038/s41598-017-14719-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663911/
https://www.ncbi.nlm.nih.gov/pubmed/29089532
http://dx.doi.org/10.1038/s41598-017-14719-9

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