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Calpain Inhibition Attenuates Adipose Tissue Inflammation and Fibrosis in Diet-induced Obese Mice
Adipose tissue macrophages have been proposed as a link between obesity and insulin resistance. However, the mechanisms underlying these processes are not completely defined. Calpains are calcium-dependent neutral cysteine proteases that modulate cellular function and have been implicated in various...
Autores principales: | Muniappan, Latha, Javidan, Aida, Jiang, Weihua, Mohammadmoradi, Shayan, Moorleghen, Jessica J., Katz, Wendy S., Balakrishnan, Anju, Howatt, Deborah A., Subramanian, Venkateswaran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663911/ https://www.ncbi.nlm.nih.gov/pubmed/29089532 http://dx.doi.org/10.1038/s41598-017-14719-9 |
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